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課程名稱 |
分子生物學
Molecular Biology |
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開課學期 |
105-1 |
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授課對象 |
醫學院 醫學檢驗暨生物技術學系 |
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授課教師 |
方偉宏 |
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課號 |
CliLab5006 |
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課程識別碼 |
424 U1200 |
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班次 |
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學分 |
4 |
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全/半年 |
半年 |
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必/選修 |
必帶 |
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上課時間 |
星期三6,7(13:20~15:10)星期四6,7(13:20~15:10) |
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上課地點 |
檢506教室檢506教室 |
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備註 |
本課程中文授課,使用英文教科書。與胡忠怡、楊雅倩、張淑媛、莊雅惠、邱浩傑、蘇剛毅、吳瑞菁、何炳慶、張百恩合開
總人數上限：50人 |
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Ceiba 課程網頁 |
http://ceiba.ntu.edu.tw/1051CliLab5006_ |
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課程簡介影片 |
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核心能力關聯 |
本課程尚未建立核心能力關連 |
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課程大綱
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課程概述 |
本課程依據課本做完整的分子生物學介紹，包括以下主題：
The Mendelian view of the world
Nucleic acid convey genetic information (I)
The importance of weak chemical interaction
The importance of high energy bonds
Weak and strong bonds determine macro molecular structure (I)
Weak and strong bonds determine macro molecular structure (II)
Exam I
The structure of DNA and RNA (I)
The structure of DNA and RNA (II)
Chromosomes, chromatin and the nucleosome (I)
Chromosomes, chromatin and the nucleosome (II)
The replication of DNA (I)
The replication of DNA (II)
The mutability and repair of DNA
Homologous recombination at the molecular level
Site-specific recombination and transposition of DNA (I)
Site-specific recombination and transposition of DNA (II)
Exam II
Mechanism of transcription (I)
Mechanism of transcription (II)
RNA splicing
Translation (I)
Translation (II)
Genetic code
Gene Regulation in bacteria
Gene Regulation in phages, Gene Regulation in Eukaryotes (I)
Gene Regulation in Eukaryotes (II)
Gene Regulation during development
Exam III
Technique of molecular Biology (I)
Technique of molecular Biology (II)
Model organisms
Products for Biotechnology
Cancer and Aging
Final Exam
考試共分四次。
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課程目標 |
完整的分子生物學介紹 |
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課程要求 |
待補 |
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預期每週課後學習時數 |
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Office Hours |
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指定閱讀 |
待補 |
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參考書目 |
Molecular Biology of the Gene, 7th ed. Watson, et al. 2013 |
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評量方式
(僅供參考) |
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週次 |
日期 |
單元主題 |
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第1週 |
9/14 |
Introduction
The Mendelian view of the world
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第2週 |
9/21,9/22 |
Nucleic acid convey genetic information
The importance of weak and strong chemical bonds/Technique of Molecular Biology
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第4週 |
10/05,10/06 |
The structure of DNA
The structure and versatility of RNA |
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第5週 |
10/12,10/13 |
Genome Structure, Chromatin and the Nucleosome (I)(II) |
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第6週 |
10/19,10/20 |
Genome Structure, Chromatin and the Nucleosome (III)
The replication of DNA (I) |
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第15週 |
12/21,12/22 |
Regulatory RNAs |
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第16週 |
12/28,12/29 |
Gene Regulation in development and evolution
System Biology
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第17週 |
1/04,1/05 |
Model organisms |
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